Orally administered
anti-emetics can be difficult for a nauseated
child to "keep down", and rectal suppositories
may not be well accepted by children. Even persistent
nausea can often be effectively controlled by
using a combination of medications tailored to
meet an individual's specific needs. Dosage forms
include transdermal gels, suppositories, lollipops,
and more.
Promethazine is commonly compounded
for topical or transdermal application to treat
nausea, vomiting, and vertigo, but this preparation
may be used as an antiemetic for cases ranging
from chemotherapy to motion sickness. The dose
is typically 25mg for adults, and the dose is
decreased for children. The gel is applied to
an area of soft skin, such as the inside of the
wrist or arm, the side of the torso, or the inside
of the thigh. For children, doses are often applied
to the inside of one wrist, and then the wrists
are rubbed together.
US Pharmacist, August 1999; 74-5 |