Androgen deficiency in the aging male (ADAM), also known as andropause, affects an estimated 1 in 200 men. Symptoms of testosterone deficiency may include:
•  weakness
•  fatigue
•  reduced libido
•  osteoporosis

A man may be considered hypogonadal at any age if total testosterone is less than 200 ng/dl, or bioavailable testosterone is less than 60 ng/dl. Basaria and Dobs of Johns Hopkins University recommend that elderly men with symptoms of hypogonadism and a total testosterone level < 300ng/dl should be started on hormone replacement.

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